Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments.
Malaria parasites (Plasmodium spp.) encounter markedly different (nutritional) environments during their complex life cycles in the digiweigh digital pocket scale mosquito and human hosts.Adaptation to these different host niches is associated with a dramatic rewiring of metabolism, from a highly glycolytic metabolism in the asexual blood stages to